Women order the estrone serum test to measure and monitor estrogen levels and help explain abnormal menstrual cycles, infertility symptoms of menopause, abnormal or heavy bleeding, infertility, or any other hormonal alterations. This blood test is also used to check for fetal-placental status during early stages of pregnancy and to evaluate feminization (the presence of female-like characteristics in males).Estrone is an estrogenic hormone secreted by the ovary as well as adipose tissue with the chemical name of 3-hydroxyestra-1,3,5-triene-17-one and the chemical formula